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Product Details:
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| Product Type: | Fermentation Bioreactor | Warranty Period: | 1 Year |
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| OEM: | Parameter Customization | Material: | 304/316L Stainless Steel |
| Heating Method: | Steam/hot Water/electrical | Usags: | Used For Various Kinds Of Microbiology Fermentation |
| Core Components: | Bioreactor With Different Sensors And Control System | Key Selling Points: | Aspetic Bioreactor ,Vaccine Fermentation,Full Automatic |
| Feeding: | Microbiology | Output: | Culture Bacterial Seed |
| Related Words: | Bioreactor Tank/Stirred Tank Bioreactor/Cell Bioreactor/Bioreactor Fermentor/Biopharmaceutical | Applicable Industries: | Bio-pharma,vaccine |
| High Light: | Microorganism Fermenter Stirred Tank,SS316L Cell Culture Stirred Tank,Vaccine Bioreactor With Jacketed |
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Cell Culture Microorganism Fermenter Stirred Tank Vaccine Bioreactor With Jacketed
Well-characterized and accelerated process development and optimization can be achieved only if the process can be sufficiently automated in a parallel miniaturised platform that is both easy to set up, scalable, and compatible with disposable technologies. So there is a need to move away from traditional bioprocess equipment and into a platform that enables high-throughput process development and optimization. That type of technology should have three key characteristics:
• miniaturization to enable faster experimental throughput at a low costs
• automation for accurate, reproducible performance of a large number of individual operations
• parallel processing to allow evaluation of a wide experimental space, resulting in process understanding.
Here I present an automated mini bioreactor technology that allows for high-throughput process development and optimization for both microbial fermentations and cell culture processes. In addition, I demonstrate the suitability of this technology by analyzing data obtained from an automated bioreactor and comparing data from laboratory- and pilot-scale bioreactors.
Main technology data for Fermentor tank
| Item | Technology specification |
| Working volume L | 5-30000L |
| material | Contact product is SS31L6 ,non-contact part is SS004 |
| Surface finish |
Inside surface is mirror polish Ra:0.3-0.5um Outside surface is mat polish Ra<0.8um |
| Working pressure | Inside shell is 0.2MPa; jacket is 0.3MPa |
| Agitation |
1).Top mechanical agitator with two layers six blade impeller ,one is for foam destroyer ,gear motor use SEW brand 2).Speed is 0-400RPM ( adjustable ) |
| Equipment of tank |
1) .using alcohol flame inoculation 2) Sterile type sampling valve and bottom flush valve 3) PH sensor ,PO2 sensor ,foam sensor ,flow meter ,temperature sensor ,Pressure sensor ,level sensor ,sight glass ,sight light etc |
| construction | Fermentation reactor tank with completely pipeline and PLC/HMI control panel |
Stainless Steel Pharmaceutical Stirred Bioreactor Reactor With High Shear Emulsifying Mixer is used for various kinds of microbiology fermentation ,our equipment adopt the top mechanical agitator system ,the speed can adjustable ,and the all parameters can control ,like the reactor temperature ,pressure PH data ,PO2 data ,foam destroyed etc .all the parameters can be recorded ,stored and printed from the control panel automatic .so it is excellent stability and convenient operation .
Stainless Steel Pharmaceutical Stirred Bioreactor Reactor With High Shear Emulsifying Mixer Tank body configuration: stainless steel SUS316L / SUS304 material; jacket temperature control, optimized diversion design; internal surface polishing, RA ≤ 0.4 μm; external surface polishing or matte treatment; large angle long strip mirror, pH electrode, do electrode, temperature electrode interface are complete; tank cover is equipped with flame inoculation port and feeding standby interface, etc.
Stainless Steel Pharmaceutical Stirred Bioreactor Reactor With High Shear Emulsifying Mixer Mixing system: top type mechanical mixing system; aseptic mechanical sealing system; DC mixing motor or AC motor; standard 2-layer flat impeller, one-stage high-efficiency defoaming paddle; optional inclined blade, curved blade, axial flow paddle, etc.; adjustable speed, digital set speed control.
Stainless Steel Pharmaceutical Stirred Bioreactor Reactor With High Shear Emulsifying Mixer Structural mode: floor type frame structure, saving space and convenient operation.
Ventilation system: deep ventilation, all stainless steel pipeline; glass rotameter display, pressure gauge display, manual valve to regulate the flow; German sartorius high-efficiency sterilization filter with stainless steel shell, filtering accuracy 0.01 μ m; external compressed air is required, equipped with high-quality water removal and pressure stabilizing device, to continuously and stably supply gas; optional mass flow controller to automatically control the air flow.
Stainless Steel Pharmaceutical Stirred Bioreactor Reactor With High Shear Emulsifying Mixer Tank pressure control: the top exhaust port is equipped with pointer type pressure gauge to display the tank pressure, and the stainless steel valve is manually adjusted; the optional inlet pressure transmitter and automatic regulating valve are equipped to realize automatic tank pressure control.
Temperature control: online detection, digital setting, automatic / manual control free switching; PT-100 temperature probe; electric heating temperature control and external cooling water automatic temperature control.
PH control: online detection, 2-way peristaltic pump automatically flows alkali or acid solution for adjustment; imported pH electrode can be sterilized by high temperature steam.
Dissolved oxygen (do): online detection, range 0-100% or 0-200%; imported do electrode, which can be sterilized by high temperature steam; it can be controlled in linkage with speed and ventilation.
Replenishment control: Standard 1-way peristaltic pump time proportional flow replenishment, flow replenishment cumulative display and record.
Defoaming mode: conductive foam electrode, automatic alarm for abnormal foam condition; standard 1 way peristaltic pump automatic / manual flow adding defoamer, cumulative volume display and record.
Control system: Siemens PLC controller real color plus touch screen, complete functions, stable operation.
Sterilization mode: in place sterilization, manual control.
Equipment features: in place sterilization, safe and reliable, no transmission leakage risk; large viewing angle longitudinal mirror observation is clear; inoculation methods are various and reliable (standard flame inoculation port, differential pressure inoculation port and other forms are optional); floor type tank is beautiful and generous; operation and disassembly are easy; special specifications can be customized.
| Control system |
Control System: on-site controller, the next crew for the Siemens S7-200 series PLC control system, it is a mature, stable, universal type of PLC, to suit a variety of automation applications, especially in manufacturing process control Application. Its modular, easy to implement distributed configuration and easy to master and so on, Siemens PLC control center has become a biological reaction process control implementation is economical and advanced control system, the system uses the touch screen display, on-site direct operations (menu type), all English menu and interface; also with the host computer for data transmission, data sampling and display tank, the system view of data analysis, reading settings. 10-inch LCD touch-sensitive screen as the display screen to display complete content-rich, user-friendly screen is simple, easy to operate. And disturbing each other. The control system can adapt to different range of sensors and actuators the output of the input signal with the signal anti-jamming system. Software: Siemens S7+ FORCE CONTORL Data collection and control module: Siemens S200 PLC controller and data collection and control module 1. Control
2. Measurement function: can feeding, bubble enemy, such as measurement of pH 4. Data Processing
5) data storage format is compatible with EXCEL, EXCEL platform can be to deal with 9. show the controller is really running against, the panel instructed the state process system, process hardware, and motion status indicator for understanding the various devices (such as peristaltic pumps, circulating pumps, heating, mixing, etc.) work status, Fault identification can be used as display |
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PC software
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BLBIO-Ver8.0 is a data recording and processing as one of the fermentation of special packages, with the English operation interface, data storage and backup, curve analysis, report generation analysis, anomaly analysis, for the fermentation and production process control and data processing bring a lot of convenience. 6. Report Printing 7. Curve printing |
1. Polishing:
Polishing is vital for tanks. Tanks should be polished wholly inside and outside.
Therefore it can ensure there is no place for the bacteria to hide in tanks.
Our polishing system consists of auto and semi-auto polishing machine and manual polishing.
Each tank is polished three times and more polish for the key place.
2. Welding:
Our argon central system for welding provides 100% pure argon to protect tanks from distorting during welding
SERVICE
We have established some overseas agent office to make the after-sales serivce already ,so it can will be service client in fast response .also in our headquarter service team ,there is a expert team which can support client in 7*24 hours .
1. Customer inquiry and consultation (URS documents)
2. Confirmation of treatment plan (DQ documents &PID Drawing)
3. Quotation offer with the technolgy document (Quotation PI )
4. Engineering and Manufacturing (Prodcution &Quality inspection )
5. Product inspection (FAT documents)
6. Delivery arrangement and loading work (full set Shipment documents)
7. After-sales service (OQ,PQ ,SAT documents)
FAQ:
1. What about your factory?
Our factory is located in Wenzhou city ,Zhejiang Province and have more than 15 years experience on machinery making.
2. How will your company control the equipment quality ?
We have a qualified expert team ,we will inspect every production proceed .also Machines will be tested in our plant before shipment .
3. How long the warranty will be?
We provide 1 years warranty for the machine running ,but we will afford whole -life service for the machine .
4. Which kind payment do your company do now ?
We accept Western Union, T/T ,D/P,D/C and irrevocable L/C payable etc.
5. Can we become your distributor in our country?
Yes, we very welcome you! More details will be discussed if you are interested in being our agent.
6. Why we choose "JOSTON "?
1. We enhance the reliability of product's quality and working life .
2. We decrease the consumption cost of the product in the ruuning.
3. We improve research personnel's ability to deliver a creative design;
4. We use leading technologies in our product development and innovation, and thereby increase the competitive advantage of products.
7. Do you supply installation equipment in oversea?
Yes, if need, we can send our engineer to your plant to help you do installation and commission.
8. Do you supply installation equipment in oversea?
Yes, if need, we can send our engineer to your plant to help you do installation and commission.
9. How can we know the order production status ?
We will arrange the person to take photo or video during manufacturing in every week to make you to know the production status.When goods are finished,we will take detailed photos or video for your checking ,after approve ,then we will arrange shipment .also you can arrange FAT in our plant when the goods is ready here
10. What is kind service do you offer before making order ?
1. according to your company URS ,we will make the design drawing accoridingly.
2. after your company approved drawing ,we will make quotation.
3. final we make agreement on payment terms ,delivery time ,package ,shipment etc.
11. how about your company after-sale serivce ?
1. We provide long-term after-sale service.
2. we can do installation and commission for the equipment in your plant if necessary .
3. Meanwhile, you can call or e-mail us to consult on any relevant question since we have a special line for after-sale service. Alternatively, you can communicate on-line with us to solve any problem.
Contact Person: Mr. Charlie Tao
Tel: 0086-13957781390
Fax: 86-577-86717290
